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|
Study
|
Outcome
|
HSCT+MSCs group
|
HSCT group
|
Time points
|
p value
|
|---|
|
Ball et al. [16]
|
NK cells (× 109/L)
|
0.497, 95% CI 0.347–0.646
|
0.252, 95% CI 0.173–0.33
|
28 days
|
= 0.02*
|
|
WBC > 1 × 109/L (days)
|
11.5, 95% CI 9.0–14.8
|
14.9, 95% CI 10.1–26.0
|
NA
|
= 0.009*
|
|
NK and T cells
|
NA
|
NA
|
3 months
|
NS
|
|
Liu et al. [22]
|
WBC (days)
|
12 (10–21)
|
12 (10–23)
|
NA
|
NS
|
|
Ghavamzadeh et al. [33]
|
WBC > 0.5 × 109/L (days)
|
17.7 (15–20)
|
17.7 (15–20)
|
NA
|
= 0.83
|
|
Mareika et al. [29]
|
(NK) cells (× 109/L)
|
0.1 (0.02–0.23)
|
0.01 (0.002–0.06)
|
100 days
|
= 0.07
|
|
B cells (× 109/L)
|
0.18 (0.11–0.43)
|
0.07 (0.02–0.19)
|
100 days
|
= 0.05*
|
|
Lee et al. [14]
|
Lymphocyte subpopulations
|
NA
|
NA
|
28, 100, 180 and 365 days
|
NS
|
|
Gonzalo-Daganzo et al. [30]
|
Lymphocyte subpopulations
|
NA
|
NA
|
NA
|
NS
|
|
Baron et al. [32]
|
T cells (× 109/L)
|
0.29 (0.00 4–0.54)
|
0.202 (0.041–0.886)
|
28 days
|
NS
|
|
Wu et al. [34]
|
Absolute lymphocyte count (× 109/L)
|
0.305 (0.196–0. 445)
|
0.256 (0.150–0.368)
|
30 days
|
= 0.35
|
|
Xiang [13]
|
The levels of serum immunoglobulins IgA, IgG, IgM, and IgE
|
1, 3, and 6 months
|
< 0.05*
|
|
The levels of T lymphocytes and B cells
|
- NA not available, NS not significant
- *Statistically significant